Grimlock helped to sniff out the "dinosaur transform static" that implicated Trypticon in the theft of world monuments. Later in the year, when Galvatron , the new Decepticon leader, had Cybertron infused with function-inverting anti-electrons, a dose of the particles gave Grimlock super-intelligence. For the first time Grimlock identified himself as "I, Grimlock". During a mission to Unicron 's disembodied head, where the Autobots were outmatched by the new Decepticon Terrorcons , Grimlock used components of Unicron's head to construct the Technobots to battle them. Combined as Computron , the Technobots felt they could not match the Terrorcons, until Grimlock transferred his super-intelligence into Computron, reverting to his old self and allowing the Autobots to claim victory.
In Pilot (Part 2) , Grimlock was freed and he transformed into his dino mode to see Bumblebee, Strongarm and Sideswipe before fighting Underbite. After a few rounds of facing Underbite, Grimlock was tossed by Underbite and was unconsciousness for a moment. When Grimlock woke up, he asked Bumblebee and his team what happened. Strongarm told Grimlock that Underbie tossed him like a lobbing ball. Grimlock was suprised to know that nobody got hurt. Grimlock went with Bumblebee, Strongarm, and Denny in his pick up truck to stop Underbite from reaching Crown city. They managed to weaken Underbite and block the bridge until Sideswipe and Russell arrived with bait to lure Underbite away. It worked, and the team managed to get Underbite near to a cliff. As they were trying to push Underbite into the bottom of the cliff, Grimlock states it was awesome doing this process but it failed as Underbite was able to eat some of the bait to recharge his strength and pushed everyone aside. When Underbite was about to crush Denny in his pick up truck, Optimus Prime grabbed on Underbite's shoulder and tossed him in the cliff to save Denny.
In December 2007, drawings were leaked on the internet of Sentinel Prime's vehicle appearance in the Transformers Animated television series. He turns into a snow plow truck.  Derrick Wyatt stated that the character was originally meant to be named Rodimus Prime , after Optimus Prime's G1 Successor. However, the idea of Rodimus being portrayed as arrogant and rude was dropped in favor of Sentinel Prime. An interesting note is that Sentinel's robot mode bears a strong resemblance to The Tick , which was a result of Townsend Coleman (the voice of the animated Tick ) being cast in the role.