Fluphenazine decanoate injection

"It belongs to the piperazine class of phenothiazines and is extremely potent; more potent than haloperidol and around fifty to seventy times the potency of chlorpromazine."

While fluphenazine certainly is a highly potent neuroleptic, I don't think it's more potent than haloperidol. Most sources I have state, that the neuroleptic potency of fluphenazine dihydrochloride administred orally or intramusculary is somewhere between 30 and 40 (maximum 50) chlorpromazine-equivalents; haloperidol is stated to have CPZeq. of 50 in all sources I have to my disposition; thus, fluphenazine is slightly less, or maximaly equaly potent, compared to haloperidol; in one publication, intramuscular fluphenazine decanoate is stated to have a potency of about 115 - 130 CPZeq's, but then again, haloperidol decanoate . is stated to have potency of 110 - 125 CPZeq.-- 00:12, 1 May 2007 (UTC)

Oral:
-Initial dose: to 10 mg orally in divided doses every 6 to 8 hours
-Maintenance dose: 1 to 5 mg/day
-Maximum dose: Up to 40 mg/day

Oral Comments:
-Maintenance doses may be given as single daily doses.
-Many patients achieve therapeutic effect with doses of less than 20 mg. Patients who are severely disturbed or inadequately controlled may require a dose of up to 40 mg/day.

Parenteral:
Fluphenazine Decanoate for Injection:
-Initial dose: to 25 mg deep IM injection into the gluteal region
-Maintenance dose: to 100 mg IM, usually every 3 to 4 weeks
-Maximum dose: 100 mg/injection

Fluphenazine HCl for Injection:
-Initial dose: to 10 mg IM, given as divided doses every 6 to 8 hours
-Maximum dose: Up to 10 mg/day

Parenteral Comments:
-Patients may switch from Fluphenazine HCl for Injection to oral formulations when symptoms are controlled. The dose of an oral formulation is approximately 2 to 3 times the dose of fluphenazine HCl for injection.

-Fluphenazine decanoate for injection may be given subcutaneously.

Uses:
-Management of manifestations of schizophrenia
-Management of patients requiring prolonged parenteral neuroleptic therapy (., patients with chronic schizophrenia)

Fluphenazine decanoate injection

fluphenazine decanoate injection

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